Publications
Henn, MR et al. Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection. PLoS Pathog. 2012
Soghoian, DZ et al. HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome. Sci Transl Med. 2012
Chang, JJ et al. Differential Regulation of TLR pathways in acute and chronic HIV-1 infection. AIDS. 2012
Lazaro, E et al. Variable HIV peptide stability in human cytosol is critical to epitope presentation and immune escape. J Clin Invest. 2011
Meditz, AL et al. Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection. J Infect Dis. 2011
Mikell, I et al. Characteristics of the earliest cross-neutralizing antibody response to HIV-1. PLoS Pathog. 2011
Chevalier, MF. et al. HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function. J Virol. 2011
Yang, Y et al. Mutational escape in HIV-1 CTL epitopes leads to increased binding to inhibitory myelomonocytic MHC class I receptors. PLos One 2010
Brockman, MA et al. Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection. J Virol. 2010
Boutwell, CT et al. Viral evolution and escape during acute HIV-1 infection. J Infect Dis. 2010
Chang, JJ et al. Innate immune activation in primary HIV-1 infection. J Infec Dis. 2010
D'Souza, MP et al. Acute HIV-1 infection: what's new? Where are we going? J Infect Dis. 2010
Rychert, J et al. Detection of HIV gp120 in plasma during early HIV infection is associated with increased proinflammatory and immunoregulatory cytokines. AIDS Res Hum Retroviruses 2010
Alter G et al. IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection. J Clin Invest 2010
Streeck, H. et al. Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T-cells. J Virol. 2009
Alter, G. et al. HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection. J Virol. 2009
Streeck, H. et al. Epidemiologically linked transmission of HIV-1 illustrates the impact of host genetics on virological outcome. AIDS. 2009
Wang, YE. et al. Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1. J Virol. 2008
Streeck, H. et al. Immune-driven recombination and loss of control after HIV superinfection. J Exp Med. 2008
Brumme, ZL. et al. Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection. J Virol. 2008
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