Publications
Streeck, H. et al. Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T-cells. J Virol. 2009
Alter, G. et al. HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection. J Virol. 2009
Streeck, H. et al. Epidemiologically linked transmission of HIV-1 illustrates the impact of host genetics on virological outcome. AIDS. 2009
Wang, YE. et al. Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1. J Virol. 2008
Streeck, H. et al. Immune-driven recombination and loss of control after HIV superinfection. J Exp Med. 2008
Brumme, ZL. et al. Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection. J Virol. 2008
Streeck, H. et al. Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T-cells. PLoS Med. 2008
Altfeld, M., Markowitz M. Acute HIV-1 infection: past lessons, current thinking, future goals. Curr Opin HIV AIDS. 2008
Rychert, J. et al. Sequence variation occurs in CD4 epitopes during early HIV infection. J Aquir Immune Defic Syndr. 2007
Alter, G. et al. Evolution of innate and adaptive effector cell functions during acute HIV-1 infection. J Infect Dis. 2007
Streeck, H. et al. Recognition of a defined region within p24 gag by CD8+ T-cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles. J Virol. 2007
Lakshmanan, V. et al. Biology of plasmacytoid dendritic cells and natural killer cells in HIV-1 infection. Curr Opin HIV AIDS. 2007
Streeck, H. et al. Loss of HIV-1-specific T-cell responses associated with very rapid HIV-1 disease progression. AIDS. 2007
Lichterfeld, M. et al. Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1) -specific CD8+ T cells after early HIV-1 infection. J Virol. 2007
Li, B. et al. Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution. J Virol. 2007
Altfeld, M. et al. HLA alleles associated with delayed progression to AIDS contribute strongly to the initial CD8 (+) T cell response against HIV-1. PLoS Med. 2006
Day, CL. et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature. 2006
Streeck, H. et al. Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection. J Infect Dis. 2006
Vogel, M. et al. Structured treatment interruptions following immediate initiation of HAART in eight patients with acute HIV-1 seroconversion. Eur J Med Res. 2006
Myer-Olson, D. et al. Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire. Blood. 2006
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